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欢迎访问北京大学张新祥教授课题组!

我们课题组致力于生化分离与生化分析相关应用,在小分子药物代谢、糖组学、单细胞检测、免疫分析、生物样品的富集分离、分子间相互作用等领域有广泛兴趣,主要集中于基于毛细管电泳、色谱分离与高分辨率质谱检测的代谢组学与糖组学研究。本课题组还在高灵敏、高特异性的新型生物化学传感器的构建,功能核酸如核酸适配体、DNA酶等的研究,功能纳米材料如磁性纳米颗粒、金纳米颗粒、碳纳米管等的合成及应用等领域累积了丰富的经验。

研究进展

5hmC-MIQuant: Ultrasensitive Quantitative Detection of 5-Hydroxymethylcytosine in Low-Input Cell-Free DNA Samples

Fang Yuan

Analytical Chemistry 2019, 92, 1, 1605–1610

A facilely synthesized glutathione-functionalized silver nanoparticle-grafted covalent organic framework for rapid and h...

Yu-Fang Ma, et al.

Nanoscale 2019, 2019,11, 5526-5534

Simultaneous multiple single nucleotide polymorphism detection based on click chemistry combined with DNA-encoded probes...

Qian-Yu Zhou, et al.

Chemical Science 2018, 2018,9, 3335-3340